Where to give in global health

Global health charities save and improve lives by preventing and treating diseases such as malaria, delivering vitamins and vaccines, and strengthening health systems in the world’s lowest-income countries. Interventions in this field are among the most cost-effective in all of philanthropy: a few dollars can protect a family from malaria or prevent a child from going blind through vitamin A deficiency.

This is also the most rigorously studied area of giving. Evaluators like GiveWell have spent tens of thousands of hours measuring cost-per-outcome, so the evidence for what actually works is unusually strong. The charities below are ranked by our composite GiveWise score, which draws on those independent evaluations.

Frequently asked questions

Why are global health charities considered so cost-effective?
The most effective interventions — insecticidal bednets, vaccines, and nutrient supplements — are inexpensive, while the disease burden they address is enormous in the poorest countries. That combination produces an exceptional amount of measurable good per dollar.
How can I be confident my donation makes a difference?
Favour charities that publish cost-per-outcome figures and are backed by randomised-trial evidence, and that are independently reviewed by evaluators such as GiveWell or Charity Navigator. Every charity below links out to its evaluator record.